Stage 2: Research & Development
Jelliffe-Pawlowski of the University of California, San Francisco together with the California Department of Public Health in the U.S. will test whether metabolic markers taken during routine newborn screening can be used to determine gestational age by developing a dating algorithm.
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University of California, San Francisco together with the California Department of Public Health will test metabolic markers during routine newborn screening.
How does your innovation work?
They will use data on around 70 metabolic markers from 750,000 newborns in the U.S. to identify those that are strongly associated with gestational age in weeks.
Planned Goals and Milestones
The algorithm will be developed using logistic regression and linear discrimination analysis, and tested for its capacity to accurately determine age in a separate group of 250,000 newborns. This algorithm could be used to determine gestational age in regions where dating is difficult, which is important for monitoring brain-related functions and development.