Updated Jan 31, 2021
An effective PZA resistance assay to reduce drug side effects and improve treatment adherence.
http://www.upch.edu.pe/portal/
Roberto Alcantara
These innovators propose to design an effective, fast and reproducible test to determine PZA resistance.
How does your innovation work?
It is important to determine PZA susceptibility in the early stages of treatment to provide a safe regimen and to improve adherence, but PZA-susceptibility assays are not adequate and lack reproducibility. These innovators propose to design a test to dete...
SEE ALLHow does your innovation work?
It is important to determine PZA susceptibility in the early stages of treatment to provide a safe regimen and to improve adherence, but PZA-susceptibility assays are not adequate and lack reproducibility. These innovators propose to design a test to dete...
Stage 2: Research & Development
There are a few reasons why the treatment of tuberculosis (TB) can fail. One of them is the lack of adherence to the DOTS strategy (directly observed treatment, short-course, recommended by the World Health Organization). The absence of fast recovery and adverse effects are commonly associated to treatment drop-out. As a result, Multi-Drug Resistant TB is emerging. Pyrazinamide (PZA), the only drug effective against latent TB, produces serious hepatic side effects.
Registered in Peruin Peru
Focus Areas:
Health
Implemented In:
Peru
1
Country Implemented In
Verified Funding
?
Planned Goals and Milestones
This project is funded under a collaborative agreement between CONCYTEC (Peru’s National Council for Science, Technology and Technological Innovation) and 49 to support 1433 innovators based in Peru.
Milestone
Oct 2014
Funds RaisedVERIFIED
$42,000
ORGANIZATIONGrand Challenges CanadaGrand Challenges Canada
as part of
Stars in Global HealthStars in Global HealthDate Unknown
Created
Date Unknown
New Country Implemented In
Peru