These innovators propose to design an effective, fast and reproducible test to determine PZA resistance.
How does your innovation work?
It is important to determine PZA susceptibility in the early stages of treatment to provide a safe regimen and to improve adherence, but PZA-susceptibility assays are not adequate and lack reproducibility. These innovators propose to design a test to dete...
SEE ALLThese innovators propose to design an effective, fast and reproducible test to determine PZA resistance.
How does your innovation work?
It is important to determine PZA susceptibility in the early stages of treatment to provide a safe regimen and to improve adherence, but PZA-susceptibility assays are not adequate and lack reproducibility. These innovators propose to design a test to determine PZA resistance. Based on our previous studies, the rate at which pyrazinoic acid (POA) is extruded from the bacteria is an accurate biomarker of PZA resistance. The ultimate goal is an automatic machine for measuring PZA resistance.
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